General Cell Based Assays
ILEX LIFE SCIENCES LLC Immuchrom Bile Acids Assay for Human Stool Samples, Photometric Assay Kit, 96 wells
The Immuchrom Bile Acids Assay Kit is photometric test that enables easy, rapid and precise quantitative determination of free bile acids in human stool samples. Calibration Range: 9 - 280 umol/L. Detection Limit: 1.91 umol/L. Principle: The quantitative determination of bile acids is carried out via their enzymatic oxidation to 3-keto steroids with the formation of thio-NADH. The resulting change in absorbance at 405 nm is determined photometrically. The concentration can be calculated from the standard curve. Application: If the absorption of bile acids in the small intestine is impaired, they are increasingly excreted in the stool, which leads to irritation of the colon and causes severe diarrhea, resulting in severe fluid loss as well as vitamin and mineral deficiencies. This is called bile acid malabsorption syndrome or chologenic diarrhea. Synonyms: steroid carboxylic acids, cholic acid, chenodeoxycholic acid.
Eurofins Discoverx cAMP Hunter™ Human MIP-1 alpha (CCR1) Gi Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human MIP-1 alpha (CCR1) Gi Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure CCR1 (GPCR) activity via decreased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Mouse LTB4R β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Mouse LTB4R β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure mLTB4R1 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter eXpress PPYR1 (NPY4R) CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0233E2CP0L)
The PathHunter PPYR1 (NPY4R) eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. pancreatic polypeptide) based activation of PPYR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged PPYR1 and EA-tagged β-Arrestin-2. Activation of PPYR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter GHSR Bioassay Kit, 10-Plate. (93-0242Y3-00142)
The PathHunter GHSR Bioassay kit provides a robust, highly sensitive, and easy-to-use functional cell based assay to measure drug potency and detect neutralizing antibodies. The bioassay kit contains all the materials needed for a complete assay including cryopreserved cells, detection reagents, cell plating reagent, positive control agonist, and assay plates. The ready-to-use cryopreserved cells have been manufactured to ensure long-term assay reproducibility, and faster implementation from characterization to lot release. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Cayman Chemical NBD-Fructose 500UG
A fluorescent derivative of fructose; has been used to monitor fructose uptake by the GLUT5 transporter in MCF-7, MDA-MB-435, and MDA-MB-231 human breast cancer cells; ex/em = 472/538 nm, respectively
Eurofins Discoverx PathHunter Human MR Nuclear Receptor Protein Interaction Cell-Based Assay Kit (CHO-K1)
The PathHunter Human MR Nuclear Receptor Stable Cell Line Protein Interaction Assay (CHO-K1) contains a stable clonal cell line used to measure MR nuclear hormone receptor activation via nuclear translocation. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human ADRB2 (W158A) ENDO-EA Pharmacotrafficking Cell-Based Assay Kit (U2OS)
The PathHunter Human ADRB2 (W158A) ENDO-EA Pharmacotrafficking Stable Cell Line Assay (U2OS) contains a stable clonal cell line used to measure pharmacochaperone-based rescue of the mutant ADRB2's trafficking to early endosomes. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx cAMP Hunter™ Human CHRM2 Gi Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human CHRM2 Gi Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure CHRM2 (GPCR) activity via decreased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Biolegend Alexa FluorR 594 anti-beta-act
Alexa Fluor 594 anti-β-actin [2F1-1]; Isotype: Mouse IgG2b, κ; Reactivity: Human, Mouse, Rat; Apps: ICC, IHC-P; Size: 100 μg
Revvity Health Sciences Inc HTRF mAb Anti-6His Eu-Conjugate, 5,000 Assay Points
HTRF mAb Anti-6His Eu-Conjugate, 5,000 Assay Points
Eurofins Discoverx PathHunter eXpress NPY2R CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0212E2CP0L)
The PathHunter NPY2R eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. peptide YY) based activation of NPY2R GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged NPY2R and EA-tagged β-Arrestin-2. Activation of NPY2R stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx cAMP Hunter™ Mouse TAAR1 Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Mouse TAAR1 Gs Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure mouse TAAR1 (GPCR) activity via increased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx cAMP Hunter eXpress FPRL1 CHO-K1 GPCR Assay, 2-Plate Kit. (95-0044E2CP2M)
The cAMP Hunter FPRL1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of FPRL1 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type FPRL1, a naturally Gi/Go coupled GPCR. Upon activation of FPRL1, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Revvity Health Sciences Inc HTRF mAb Anti-6His XL665-Conjugate, 5,000 Assay Points
HTRF mAb Anti-6His XL665-Conjugate, 5,000 Assay Points